Pacing Guides
Five schedules follow, for the five formats this book is actually adopted into. Each is a real plan rather than an even division of 28 by the number of weeks — an even division is what produces a course that spends as long on skin as on the nephron and then wonders why the class fails the renal exam.
Take any of these and change it. They are starting points with the hard decisions already made and stated out loud, which is the slow part.
Before you build a schedule: three numbers
1 · There is more book than there are hours. The difficulty index at the end of this page estimates the class hours each chapter genuinely needs. The total is 113 lecture hours. A standard two-semester, three-credit lecture sequence gives you about 90. You are 23 hours short before you start, which means every workable schedule is a set of deliberate cuts. The guides below make those cuts explicitly so you can argue with them.
2 · Reading load is the constraint students actually hit. Chapters run 10,000–15,000 words. Plan with these figures:
| Week's assignment | Words | Printed pages (~450 w/pg) | First-pass reading | Total student time incl. review |
|---|---|---|---|---|
| One chapter | ~12,000 | 25–30 | 75–100 min | 3.5–4.5 h |
| Two chapters | ~24,000 | 50–60 | 150–200 min | 7–9 h |
| Half chapter | ~6,000 | 12–15 | 40–50 min | 2 h |
A two-chapter week costs a student more than the 6–9 hours per week a three-credit course is nominally entitled to, once the Review sections and the Case File entry are counted. Two-chapter weeks are sometimes unavoidable. Three in a row is a mistake you will pay for on the next exam.
3 · The lecture-to-active-learning ratio matters more as the format compresses. Most instructors get this backwards under time pressure: the tighter the schedule, the more of the remaining class time should be active, because the exposition is already in the book and supervised reasoning practice is not. Recommended splits appear with each guide.
The two conceptual walls
Two places in this book reliably stop a class. Every schedule below is built around them, and if you take nothing else from this page, take their placement.
Wall 1 · Excitation–contraction coupling (Chapter 9, §9.4–8.6). Action potential → T-tubule → dihydropyridine receptor → ryanodine receptor → calcium release → troponin → cross-bridge cycle → ATP hydrolysis → detachment → SERCA reuptake. It is eight coupled steps in which every step is a prerequisite for the next, it is the first genuinely mechanistic content in the course, and it is where students who have been passing by memorization discover that memorization has stopped working. Some of them conclude they are bad at science. Say out loud, in advance, that this chapter is the hardest thing so far and that struggling with it is the normal experience — that single sentence measurably reduces withdrawals.
Wall 2 · The countercurrent multiplier (Chapter 26, §26.5–22.6). The loop of Henle generates a medullary osmotic gradient it also depends on, which is a circular explanation until the student sees that the multiplication is a time-course, not a steady state. It is the only place in a first-year course that requires holding a self-reinforcing loop in mind, and it lands late in the second semester when students are tired.
Placement rules that work:
- Never put a wall in the same week as an exam. Students triage, and they triage away from the thing that is hard and toward the thing that is graded on Friday.
- Give each wall a full week with no competing chapter, and put the exam that covers it at least one week later.
- Never put a wall in the last two weeks of a term.
- Both walls reward the same intervention: build them once, slowly, at the board, forwards; then have students rebuild them backwards from a consequence ("the patient's serum calcium is high — walk back up the chain"). Backwards is where you find out whether they have it.
WHERE THE TWO WALLS FALL IN EACH FORMAT
═══════════════════════════════════════════════════════════════════════════
FORMAT │ WALL 1 (Ch 8, E-C coupling) │ WALL 2 (Ch 22, countercurrent)
──────────────────────────┼─────────────────────────────┼──────────────────────────────
2-semester (15 + 15) │ S1 wk 8–9 ██ full 2 weeks │ S2 wk 11–12 ██ full 2 weeks
2-quarter (10 + 10) │ Q1 wk 6–7 ██ 1.5 weeks │ Q2 wk 7–8 ██ 1.5 weeks
1-semester survey (16) │ wk 7 ██ 1 week │ wk 16 ▓ SURFACE ONLY
Accelerated (10) │ ─ omitted / assigned ─ │ wk 9 ██ 1 week
Summer intensive (6) │ wk 2 ▒ 2 days │ wk 5 ▒ 2 days
──────────────────────────┴─────────────────────────────┴──────────────────────────────
██ taught fully ▓ concept only, no mechanism ▒ compressed, expect attrition
RULE: exam covering a wall sits ≥1 week AFTER the wall week.
Wall week contains no second chapter and no exam.
Figure IC.2 — Placement of the two hardest conceptual walls across the five course formats.
Described: A table showing when each course format reaches its two hardest topics. In the two-semester format, excitation–contraction coupling in Chapter 9 occupies weeks 8 and 9 of semester 1 and the countercurrent multiplier in Chapter 26 occupies weeks 11 and 12 of semester 2, each taught fully across two weeks. The two-quarter format gives each about a week and a half, in weeks 6 to 7 of quarter 1 and weeks 7 to 8 of quarter 2. The one-semester survey gives Chapter 9 a single week in week 7 and reaches Chapter 26 only in week 16, where the countercurrent mechanism is presented as a concept without its mechanism. The accelerated allied-health format omits Chapter 9 from class and assigns it as reading, but teaches Chapter 26 fully in week 9. The summer intensive compresses each wall into roughly two days, in weeks 2 and 5, and should expect attrition there. The governing rules are that any exam covering a wall must fall at least one week after it, and that a wall week contains no second chapter and no exam.
Guide 1 · Two semesters, 15 weeks each — the standard majors sequence
The default. Three lecture hours and one three-hour lab per week, Chapters 1–16 in Semester 1 and 15–28 in Semester 2. Four exams per semester including the final.
Lecture : active learning — 60 : 40. In a 50-minute period that is roughly 30 minutes of exposition in two blocks with a 5-minute retrieval or prediction task between them, and a closing 10 minutes of application — a Case File prompt, a "predict the consequence" item, or two Level 3 review questions worked in pairs.
Semester 1 · Chapters 1–16
| Week | Chapters | Topics | Lab | Assessment | Case File entries due |
|---|---|---|---|---|---|
| 1 | 1 | Levels of organization; the 11 systems; homeostasis and feedback; anatomical language | Safety, microscopy, anatomical position and planes | Diagnostic pre-test (ungraded) | 1 |
| 2 | 2 | Atoms, bonds, water, pH, buffers; the four organic families | The cell: microscopy and prepared slides | Quiz 1 (Ch 1) | 2 |
| 3 | 3 | Membrane structure and transport; organelles; the cell cycle | Diffusion, osmosis, tonicity | — | 3 |
| 4 | 4 | Epithelia; connective tissue; junctions; membranes; repair | Histology I — the four tissue types | Exam 1 · Ch 1–4 | 4 |
| 5 | 5 | Epidermal strata; dermis; appendages; thermoregulation; burns | Integument and skin histology | Quiz 2 (Ch 5) | 5 |
| 6 | 6 | Bone as a composite; osteons; remodeling; calcium homeostasis | Bone tissue histology; long bone structure | — | 6 |
| 7 | 7 | Axial and appendicular skeleton; joint classes; movements | Skeleton I (axial) and Skeleton II (appendicular) | Quiz 3 (Ch 6) | 7 |
| 8 | 8 §9.1–8.5 | Wall 1. Muscle architecture; sarcomere; NMJ; excitation–contraction coupling | Skeletal muscle histology; articulations | Exam 2 · Ch 5–7 | — |
| 9 | 8 §9.6–8.9 | Cross-bridge cycle; twitch and tetanus; motor unit recruitment; fiber types; energy systems | Muscle physiology — grip force, fatigue, EMG if available | — | 8 |
| 10 | 9 | Naming logic; lever systems; muscles of head, neck, trunk, limbs | Muscles I (axial) | Quiz 4 (Ch 8) | 9 |
| 11 | 10 | Neuron structure; glia; resting potential; action potential; synapses | Muscles II (appendicular) · Lab Practical 1 | Exam 3 · Ch 8–9 | 10 |
| 12 | 11 | Brain organization; cerebrum; diencephalon; brainstem; cerebellum; meninges and CSF; spinal cord | Nervous tissue histology | Quiz 5 (Ch 10) | 11 |
| 13 | 12 | Sensory receptors; dermatomes; cranial and spinal nerves; the autonomic divisions | Brain and spinal cord (sheep brain or model) | — | 12 |
| 14 | 13 | Vision; hearing and equilibrium; taste and smell | Reflexes and sensory testing | Quiz 6 (Ch 11–12) | 13 |
| 15 | 14 | Hormone classes and mechanisms; hypothalamic–pituitary axis; thyroid; adrenal; pancreas | Special senses · Lab Practical 2 | Final · cumulative, weighted to Ch 10–14 | 14 |
Exam placement rationale. Exam 1 after Chapter 4 catches the students still treating this as a memorization course while intervention is possible; returning it with a study-method conversation in week 5 is the highest-value fifteen minutes in the semester. Exam 2 covers the light musculoskeletal material and sits during the first hard week so Chapter 9 has two clean weeks after it. Exam 3 lands a full week after Wall 1 ends.
Where students historically struggle in this format.
- Chapter 9 — Wall 1. Two weeks, no competing content, and the exam a week later. See above.
- Chapter 16 (endocrine) — it arrives in the last week, when students are exhausted, and carries the heaviest memorization load in Semester 1 (roughly forty hormones with source, target, trigger, and effect) while being load-bearing for Chapters 24–28. The fix is one structural table — hormone / gland / stimulus / target / action / feedback loop — built collaboratively in class rather than delivered, with Appendix F as the reference. Teach three axes completely (thyroid, adrenal, calcium) and let the rest be table work.
- Chapter 4 (tissues) — the difficulty is perceptual, not conceptual. Students can recite the classification and cannot recognize a slide. This is a lab problem with a lab solution; see Laboratory Alignment.
Semester 2 · Chapters 17–33
| Week | Chapters | Topics | Lab | Assessment | Case File entries due |
|---|---|---|---|---|---|
| 1 | 15 | Plasma; erythropoiesis; leukocytes; hemostasis; ABO and Rh | Hematology: hematocrit, differential, blood typing | Diagnostic review quiz (Ch 1–14) | 15 |
| 2 | 16 §18.1–16.5 | Heart position and coverings; chambers; valves; coronary circulation; the cardiac cycle | Heart anatomy — sheep heart or model | — | — |
| 3 | 16 §18.6–16.9 | Conduction system; ECG; cardiac output; Starling's law; regulation | ECG recording and interpretation | Exam 1 · Ch 15–16 | 16 |
| 4 | 17 §19.1–17.4 | Vessel wall structure; the circuits; hemodynamics; pressure, flow, resistance | Blood vessel identification | — | 17 |
| 5 | 17 §19.5–17.9 | Capillary exchange and Starling forces; MAP regulation; baroreflex; shock | Blood pressure and pulse measurement | Quiz 1 (Ch 17) | — |
| 6 | 18 | Lymphatic drainage; innate defense; humoral and cellular immunity; inflammation; hypersensitivity | Lymphatic organs and histology | — | 18 |
| 7 | 19 §22.1–19.5 | Airways; alveolar structure; mechanics of ventilation; lung volumes | Respiratory anatomy and spirometry | Exam 2 · Ch 17–18 | 19 |
| 8 | 19 §22.6–19.9 | Gas laws; O₂ and CO₂ transport; the dissociation curve; control of breathing | Gas exchange and breath-hold experiments | Quiz 2 (Ch 19) | — |
| 9 | 20 | GI anatomy; motility; secretion; digestion and absorption; liver | Digestive anatomy; enzyme activity | — | 20 |
| 10 | 21 | Nutrients; glycolysis to oxidative phosphorylation; fed and fasted states; energy balance | Metabolism and calorimetry · Lab Practical 3 | Quiz 3 (Ch 20) | 21 |
| 11 | 22 §26.1–22.4 | Kidney and nephron anatomy; filtration and GFR; tubular reabsorption and secretion | Urinary anatomy and urinalysis | Exam 3 · Ch 19–21 | — |
| 12 | 22 §26.5–22.9 | Wall 2. Countercurrent multiplier; ADH and aldosterone; clearance; micturition | Renal physiology problems; simulated urinalysis cases | — | 22 |
| 13 | 23, 24 | Gonadal anatomy; gametogenesis; the ovarian and uterine cycles; fertilization; placenta; parturition | Reproductive anatomy; embryology models | Quiz 4 (Ch 22) | 23, 24 |
| 14 | 25, 26 | DNA to protein; Mendelian and polygenic inheritance; pedigrees; system-by-system aging | Genetics and inheritance · Lab Practical 4 | — | 25, 26 |
| 15 | 27, 28 | Fluid compartments; sodium, potassium, calcium; acid–base and the four disturbances; capstone integration | Acid–base case workshop | Final · cumulative, weighted to Ch 19–27 · Case File capstone due | 27, 28 |
A strong recommendation about Chapter 31
The schedule above is the conventional one and it is wrong in one respect, which is worth fixing. Chapter 31 — fluid, electrolyte, and acid–base balance — is the highest-yield chapter in the book for nursing and allied health, and putting it in week 15 guarantees it is taught badly and learned worse.
Swap it forward. Teach Chapter 31 in week 13, immediately after Chapter 26, while renal handling of sodium, water, and hydrogen is still live. Move Chapters 27–30 to weeks 14 and 15. Reproduction, development, genetics, and aging tolerate compression far better than acid–base does, and 23–26 are largely descriptive where 27 is entirely mechanistic. The cost is that Chapter 28 loses depth; the benefit is that your students can interpret an arterial blood gas in June.
Where students historically struggle in this format.
- Chapter 26 — Wall 2, discussed above. Two weeks; exam a week later; teach filtration and reabsorption completely before you touch the loop.
- Chapter 22 §22.7 (the oxyhemoglobin dissociation curve) — students memorize "right shift means unloading" without seeing that the curve's shape is the mechanism. Ask what would happen if it were a straight line; half the class discovers cooperativity on their own.
- Chapter 20 (immunity) — the vocabulary load is enormous and the conceptual core is small. Teach four things properly (innate versus adaptive; antigen presentation; clonal selection; the memory response) and hang everything else off them. Students drown here because they treat two hundred terms as equally important and nobody tells them otherwise.
Guide 2 · Two quarters, 10 weeks each
Same content, two-thirds the time. The honest statement of what happens: a quarter system does not compress a semester course, it deletes about a third of it. Decide what you are deleting or the last three weeks will decide for you.
What gets compressed (taught, but at lower resolution): Chapter 2 to the sections that Chapter 3 needs; Chapters 6 and 7 into one week with joint classification reduced to a table; Chapter 10 to naming logic plus the muscles your lab practical actually tests; Chapters 13 and 15 into one week; Chapters 27–30 into one week and a half.
What gets cut (assigned as reading, not on the exam): most Development sidebars; every Advanced Topic section; Chapter 15's chemical senses; Chapter 23's enzymology; Chapter 29 beyond pedigrees and polygenic risk.
Lecture : active learning — 55 : 45. Counterintuitive under time pressure, and correct. The lecture content is in the book; the reasoning practice is not.
Quarter 1 · Chapters 1–16
| Week | Chapters | Topics | Lab | Assessment | Case File entries due |
|---|---|---|---|---|---|
| 1 | 1, 2 | Organization; homeostasis and feedback; anatomical language; bonds, water, pH | Safety, microscopy, terminology | — | 1, 2 |
| 2 | 3 | Membrane transport; organelles; cell cycle | Diffusion and osmosis | Quiz 1 | 3 |
| 3 | 4 | The four tissue types; junctions; repair | Histology — four tissue types | Exam 1 · Ch 1–3 | 4 |
| 4 | 5, 6 | Skin structure and thermoregulation; bone as composite; remodeling | Integument and bone histology | — | 5, 6 |
| 5 | 7 | Axial and appendicular skeleton; joints | Skeleton and articulations | Quiz 2 | 7 |
| 6 | 8 §9.1–8.5 | Wall 1. Sarcomere; NMJ; excitation–contraction coupling | Muscle histology | Exam 2 · Ch 4–7 | — |
| 7 | 8 §9.6–8.9, 9 | Cross-bridge cycle; motor units; fiber types; muscle naming and levers | Major muscles · Practical 1 | — | 8, 9 |
| 8 | 10 | Resting potential; action potential; synaptic transmission | Nervous tissue histology | Quiz 3 (Ch 8) | 10 |
| 9 | 11, 12 | Brain regions; spinal cord; sensory receptors; autonomic divisions | Sheep brain; reflexes | Exam 3 · Ch 8–10 | 11, 12 |
| 10 | 13, 14 | Vision and hearing in outline; hormone mechanisms; the major axes | Special senses · Practical 2 | Final · cumulative | 13, 14 |
Quarter 2 · Chapters 17–33
| Week | Chapters | Topics | Lab | Assessment | Case File entries due |
|---|---|---|---|---|---|
| 1 | 15 | Plasma; formed elements; hemostasis; blood groups | Hematology and typing | — | 15 |
| 2 | 16 | Heart anatomy; cardiac cycle; conduction; ECG; cardiac output | Sheep heart; ECG | Quiz 1 | 16 |
| 3 | 17 | Vessels; hemodynamics; capillary exchange; MAP regulation | Vessels; blood pressure | Exam 1 · Ch 15–16 | 17 |
| 4 | 18 | Lymphatics; innate and adaptive immunity; inflammation | Lymphatic organs | — | 18 |
| 5 | 19 | Ventilation mechanics; lung volumes; gas transport; control of breathing | Respiratory anatomy and spirometry | Quiz 2 (Ch 17–18) | 19 |
| 6 | 20, 21 | GI motility, secretion, absorption; metabolic pathways in outline; fed and fasted states | Digestion and enzyme activity | Exam 2 · Ch 17–19 | 20, 21 |
| 7 | 22 §26.1–22.4 | Nephron anatomy; filtration and GFR; reabsorption and secretion | Urinary anatomy and urinalysis · Practical 3 | — | — |
| 8 | 22 §26.5–22.9 | Wall 2. Countercurrent multiplier; ADH; aldosterone; clearance | Renal physiology problems | Quiz 3 (Ch 20–21) | 22 |
| 9 | 27, 23 | Fluid compartments; sodium and potassium; acid–base disturbances; reproductive anatomy in outline | Acid–base workshop | Exam 3 · Ch 22 | 27, 23 |
| 10 | 24, 25, 26, 28 | Fertilization to birth in outline; pedigrees and polygenic risk; aging by system; capstone | Genetics · Practical 4 | Final · Case File capstone due | 24, 25, 26, 28 |
The three chapters students most reliably struggle with in this format: Chapter 9 (Wall 1, now with only a week and a half); Chapter 26 (Wall 2, same); and — specific to the quarter system — Chapter 16, because endocrine falls in the final week of Quarter 1 and is then assumed by Chapters 24–28 in a quarter the student has not started yet. If your program allows it, move Chapter 16 to Quarter 2 week 1 and open the second quarter with hormones. It costs Quarter 1 nothing and it repairs the worst seam in the sequence.
Guide 3 · One-semester survey, 16 weeks
For non-majors, dental hygiene, health science, and pre-nursing preparation courses. Built on the Core 16 from Learning Paths: Chapters 1, 3, 4, 5, 6, 7, 9, 11, 12, 16, 17, 18, 19, 22, 23, 26. The goal is a durable mental model, not comprehensive nomenclature — and the single most common way this course fails is that the instructor, trained on the majors sequence, teaches a thinner version of it instead of a different one.
Teach mechanism; cut nomenclature ruthlessly. A survey student who can explain why a diuretic lowers blood pressure but cannot name the sartorius has learned the more valuable thing.
Lecture : active learning — 50 : 50.
| Week | Chapters | Topics | Lab | Assessment | Case File entries due |
|---|---|---|---|---|---|
| 1 | 1 | Levels of organization; the 11 systems; homeostasis; directional terms | Terminology and body regions | Pre-test | 1 |
| 2 | 2 (§2.1, §2.5, §2.6), 3 | Atoms and bonds; pH; macromolecules; membrane and transport | Microscopy; the cell | — | 2 |
| 3 | 3 | Organelles; osmosis and tonicity; the cell cycle | Diffusion and osmosis | Quiz 1 | 3 |
| 4 | 4 | The four tissue types; membranes; repair | Histology — four tissue types | Exam 1 · Ch 1–4 | 4 |
| 5 | 5 | Skin layers; appendages; thermoregulation; wound healing | Integument | — | 5 |
| 6 | 6, 7 | Bone structure and remodeling; the skeleton in outline; joint types and movements | Skeleton and joints | Quiz 2 | 6, 7 |
| 7 | 8 | Wall 1, single week. Sliding filaments; excitation–contraction coupling; motor units; fiber types | Muscle physiology (no histology practical) | — | 8 |
| 8 | 10 | Neuron structure; the action potential as a wave, not a wire; synapses | Nervous tissue and reflexes | Exam 2 · Ch 5–8 | 10 |
| 9 | 11 | Brain regions and their jobs; spinal cord; CSF and protection | Brain models | Quiz 3 | 11 |
| 10 | 14 | Hormone classes; negative feedback axes; thyroid, adrenal, pancreas | Endocrine histology | — | 14 |
| 11 | 15 | Blood composition; oxygen carriage; clotting; blood groups | Hematology and typing | Quiz 4 | 15 |
| 12 | 16 | Heart anatomy; the cardiac cycle; conduction and ECG basics | Heart anatomy | — | 16 |
| 13 | 17 | Vessels; blood pressure and what raises it; capillary exchange | Blood pressure measurement | Exam 3 · Ch 10–16 | 17 |
| 14 | 19 | Ventilation; gas exchange; transport; why we breathe | Spirometry | Quiz 5 | 19 |
| 15 | 20 | GI tract organization; secretion; digestion and absorption; the liver | Digestive anatomy; enzymes | — | 20 |
| 16 | 22 | Nephron function; filtration; what the kidney regulates. Countercurrent as concept only | Urinalysis | Final · cumulative · Case File due | 22 |
Swap-ins if your syllabus has room or names them: Chapter 20 for week 15 in a pre-nursing section; Chapter 27 for dental hygiene and general education; Chapter 31 for week 16 if students continue into nursing — in which case teach 22 and 27 as one unit at survey depth.
The three chapters students most reliably struggle with in this format: Chapter 9, which gets one week and needs two — teach the cross-bridge cycle and the calcium switch, and let the molecular detail of the T-tubule–SR junction go. Chapter 16, because survey students have no prior framework for chemical signaling — build the generic axis (hypothalamus → pituitary → gland → hormone → target → negative feedback) once and reuse it three times rather than teaching three separate axes. And Chapter 4, for the same perceptual reason as always.
Wall 2 is not taught in this format. State the medullary gradient as a fact, show that ADH opens water channels in the collecting duct, and let students explain why concentrated urine is possible without deriving how the gradient is built. This is the right call at survey depth and you should not feel bad about it.
Guide 4 · Accelerated allied health / EMT–paramedic, 10 weeks
For programs where A&P is a gateway module inside a larger certificate: EMT and paramedic, respiratory therapy, surgical technology, medical assisting, and accelerated practical nursing. Uses the accelerated order from Learning Paths: 1 → 3 → 4 → 10 → 11/12 → 15 → 16 → 17 → 19 → 22 → 27 → 28.
The organizing principle is perfusion. Prehospital and acute care is airway, breathing, circulation, perfusion, and neurologic status, and this sequence front-loads exactly the physiology that explains why each of those fails.
Lecture : active learning — 45 : 55. These students are motivated by cases and bored by taxonomy. Run a scenario every session.
| Week | Chapters | Topics | Lab | Assessment | Case File entries due |
|---|---|---|---|---|---|
| 1 | 1, 2 (§2.5) | Homeostasis and feedback; anatomical language; body cavities; pH and buffers | Terminology; body regions; vital signs technique | Pre-test | 1 |
| 2 | 3, 4 | Membrane transport; osmosis and tonicity; the four tissue types; repair and scar | Microscopy; osmosis with IV fluid tonicity | Quiz 1 | 3, 4 |
| 3 | 10 | Resting potential; action potential; synapses; why local anesthetics work | Reflex testing; sensory levels | — | 10 |
| 4 | 11, 12 | Brain regions; ICP and the Monro–Kellie doctrine; spinal cord and dermatomes; autonomic divisions | Neuro exam; Glasgow Coma Scale mapped to anatomy | Exam 1 · Ch 1–10 | 11, 12 |
| 5 | 15 | Oxygen carriage; hematocrit; hemostasis; blood groups and transfusion | Hematology; typing | Quiz 2 | 15 |
| 6 | 16 | Cardiac anatomy; the cardiac cycle; conduction; ECG; cardiac output | Heart anatomy; 12-lead placement and rhythm strips | — | 16 |
| 7 | 17 | Hemodynamics; MAP, SVR, preload, afterload; capillary exchange; the four shock categories | Blood pressure; orthostatic vitals | Exam 2 · Ch 11–16 | 17 |
| 8 | 19 | Ventilation mechanics; dead space; V/Q mismatch; O₂ and CO₂ transport; control of breathing | Spirometry; capnography if available | Quiz 3 | 19 |
| 9 | 22 | Wall 2. Nephron function; GFR and perfusion pressure; the countercurrent multiplier; RAAS | Urinalysis; fluid-balance calculations | — | 22 |
| 10 | 27, 28 | Fluid compartments; sodium and potassium emergencies; the four acid–base disturbances; capstone | Acid–base and ABG workshop | Final · cumulative · Case File capstone due | 27, 28 |
Supporting chapters, assigned as reading modules with short quizzes rather than lecture: 5 (burns, rule of nines), 6–7 (fractures, immobilization), 8–9 (compartment syndrome, crush injury), 14 §16.4 and §16.6 (adrenal, pancreas), 18 (sepsis, anaphylaxis), 20 (abdominal quadrants, GI bleeding).
The three chapters students most reliably struggle with in this format: Chapter 26, which is Wall 2 in a single week — teach GFR as a pressure problem first, since these students already understand perfusion, and the nephron becomes an application of something they own. Chapter 31, because it arrives last and is the whole point — protect it, and consider running it as a two-session workshop with real gas values rather than as lecture. And Chapter 11, which surprises people: accelerated students expect anatomy and get electrochemistry in week 3. Warn them, and anchor every step to a drug or a finding — lidocaine blocks sodium channels, hyperkalemia depolarizes the resting membrane, hypocalcemia lowers the threshold.
Chapter 9 is deliberately omitted from class time. Excitation–contraction coupling is assigned reading and appears on no exam. This is the cut that buys the schedule, and it is the right one for this audience: cardiac excitation–contraction coupling gets taught properly in Chapter 18 where it matters to them.
Guide 5 · Summer intensive, 6 weeks, two-semester content
Some programs run the full two-semester sequence as one six-week block — typically four hours of lecture and four of lab per day, five days a week. People do complete it. Here is the schedule, and then the warning, which your students should get in writing on day one.
Lecture : active learning — 50 : 50, with mandatory movement. Four-hour blocks fail as lecture regardless of quality. Structure every block as 25 minutes exposition, 10 minutes retrieval or application, repeat, with a real break each hour.
| Week | Chapters | Topics | Lab | Assessment | Case File entries due |
|---|---|---|---|---|---|
| 1 | 1–4 | Organization and homeostasis; chemistry; cells and transport; the four tissues | Microscopy; osmosis; histology of four tissues | Exam 1 · Ch 1–4 (Fri) | 1–4 |
| 2 | 5–9 | Skin; bone and remodeling; skeleton and joints; Wall 1; muscles and levers | Integument; bone; skeleton; muscle histology · Practical 1 | Quiz (Ch 5–7) | 5–9 |
| 3 | 10–14 | Neurons and action potentials; brain and cord; PNS and autonomics; senses; hormones | Sheep brain; reflexes; senses; endocrine histology | Exam 2 · Ch 5–14 (Fri) | 10–14 |
| 4 | 15–18 | Blood; heart and ECG; vessels and blood pressure; immunity | Hematology; sheep heart; ECG; BP · Practical 2 | Quiz (Ch 15–16) | 15–18 |
| 5 | 19–22 | Ventilation and gas transport; GI; metabolism; Wall 2 | Spirometry; digestion; urinalysis | Exam 3 · Ch 15–21 (Fri) | 19–22 |
| 6 | 23–28 | Reproduction; development; genetics; aging; fluid and acid–base; capstone | Genetics; acid–base workshop · Practical 3 | Final · cumulative · Case File capstone | 23–28 |
An honest warning about the six-week format
Say this to your students, and mean it. In six weeks you can transmit the content and you can assess it. What you cannot do is space it, and spacing is not a study preference — it is the mechanism by which durable memory is formed. A student who learns Chapter 9 on a Tuesday and is tested on it nine days later will pass the exam and will not have it in October, because the retrieval schedule that consolidates knowledge across weeks physically did not happen.
What is genuinely lost: long-term retention, which is the entire point if this course gates pathophysiology or pharmacology; slide recognition, which is perceptual learning and needs repeated exposure across days; and the Case File's central effect, which comes from building a model over months rather than assembling one in a fortnight.
Recommend this format to two groups only: students repeating the course who already have a first pass in memory, and students with strong recent biology and chemistry and no employment during the term. For everyone else, be direct that a compressed course is a scheduling convenience purchased with retention, and that they will pay for it in the next course. Some of them will take it anyway, which is their right — but they should choose it knowingly.
If you must teach it, protect two things above all: the Friday exams stay cumulative, and the Case File entries stay due daily. Those are the only two spacing mechanisms the format permits.
Chapter difficulty and time index
Ratings are 1 (light) to 5 (severe). Conceptual difficulty is how much mechanism a student must hold at once; memorization load is sheer volume of names, values, and lists; hours is lecture contact time to teach the chapter properly, not to survey it. Totals assume a three-credit lecture with a separate lab.
| Ch | Title | Conceptual | Memorization | Class hours | Note |
|---|---|---|---|---|---|
| 1 | Orientation | 2 | 3 | 3 | Feedback loops are the whole chapter; terminology is drill |
| 2 | Chemistry | 3 | 2 | 3 | Cut to what Chapter 3 needs if pressed |
| 3 | Cells | 3 | 3 | 4 | Transport mechanisms are reused for the rest of the book |
| 4 | Tissues | 2 | 4 | 4 | Difficulty is perceptual — a lab problem |
| 5 | Integumentary | 1 | 2 | 2 | The easiest chapter; use it to build confidence |
| 6 | Bone tissue | 2 | 3 | 3 | Calcium homeostasis is the load-bearing part |
| 7 | Skeleton, joints | 1 | 5 | 5 | Pure nomenclature; entirely a lab and drill problem |
| 8 | Muscle physiology | 5 | 3 | 6 | Wall 1. Two full weeks in any semester format |
| 9 | Muscular system | 1 | 5 | 5 | Teach naming logic, then let the tables do the work |
| 10 | Neurons | 5 | 3 | 5 | Reused in Chapters 9, 15, 16, 18, 26 — never shortchange it |
| 11 | CNS | 3 | 5 | 5 | Vast vocabulary, modest mechanism |
| 12 | PNS, autonomic | 3 | 4 | 4 | Autonomic pharmacology logic pays off all semester |
| 13 | Special senses | 3 | 4 | 4 | Transduction is the concept; the rest is anatomy |
| 14 | Endocrine | 4 | 5 | 5 | Heaviest table load in Semester 1; load-bearing for 21–24 |
| 15 | Blood | 2 | 3 | 3 | Concrete, quantitative, well liked |
| 16 | Heart | 4 | 3 | 5 | The pivot chapter of Semester 2 |
| 17 | Vessels | 4 | 3 | 5 | Pressure–flow–resistance is the reusable idea |
| 18 | Immunity | 4 | 4 | 4 | Small core, enormous vocabulary — say which is which |
| 19 | Respiratory | 4 | 3 | 5 | The dissociation curve is the hard 30 minutes |
| 20 | Digestive | 2 | 4 | 4 | Long, but conceptually gentle |
| 21 | Metabolism | 4 | 3 | 4 | Teach fed versus fasted states, not pathway intermediates |
| 22 | Urinary | 5 | 3 | 6 | Wall 2. Two full weeks in any semester format |
| 23 | Reproductive | 2 | 4 | 3 | Cycle regulation is the only hard part |
| 24 | Development | 2 | 3 | 3 | Compresses well |
| 25 | Genetics | 3 | 2 | 3 | Pedigrees and probability; compresses well |
| 26 | Aging | 1 | 2 | 2 | Best used as a cumulative review of every prior system |
| 27 | Fluid, acid–base | 5 | 2 | 5 | Highest yield per hour in the book. Do not schedule it last |
| 28 | Capstone | 3 | 1 | 3 | One class period plus Case File presentations |
| Total | 113 | Against roughly 90 available hours in a two-semester sequence |
How to read the gap. You are 23 hours short. The cheapest hours to recover: Chapters 7 and 10, by moving nomenclature to lab and drill (~5 h); Chapters 23 and 27–30 at survey depth (~6 h); Chapter 15 without the chemical senses (~2 h); Chapter 2 cut to what Chapter 3 needs (~1.5 h); Chapter 12 taught by region rather than by nucleus (~2 h). That is roughly 16. The remaining 7 come out of review sessions, which is fine — or out of Chapters 9, 26, and 31, which is not.
Next: Laboratory Alignment — the lab sequence mapped to chapters, with low-cost and no-dissection alternatives.